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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
40.91
Human Site:
T258
Identified Species:
75
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
T258
V
D
P
L
K
R
A
T
I
K
D
I
R
E
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
T260
V
D
P
M
K
R
A
T
I
K
D
I
R
E
H
Dog
Lupus familis
XP_546691
722
81319
T428
V
D
P
L
K
R
A
T
I
K
D
I
R
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
T258
V
D
P
L
K
R
A
T
I
K
D
I
R
E
H
Rat
Rattus norvegicus
Q09137
552
62239
T258
V
D
P
L
K
R
A
T
I
K
D
I
R
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
T229
V
D
P
M
K
R
A
T
I
R
D
I
R
E
H
Chicken
Gallus gallus
Q9IA88
798
88848
T267
V
D
P
T
K
R
I
T
I
S
Q
I
K
Q
H
Frog
Xenopus laevis
NP_001088426
560
64038
T269
V
D
P
M
K
R
A
T
I
K
D
I
R
E
H
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S300
L
E
P
S
R
R
L
S
M
E
Q
I
C
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
G232
L
F
R
K
I
K
S
G
V
F
P
I
P
E
Y
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
T329
V
D
P
M
K
R
A
T
I
K
D
V
I
A
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
G255
L
F
K
K
I
K
G
G
I
Y
T
L
P
S
H
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S296
V
N
P
L
N
R
I
S
I
H
E
I
M
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
86.6
60
93.3
20
N.A.
N.A.
13.3
73.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
73.3
100
73.3
N.A.
N.A.
46.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
62
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
70
0
0
0
0
0
0
0
0
62
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
8
0
0
62
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
16
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
77
% H
% Ile:
0
0
0
0
16
0
16
0
85
0
0
85
8
0
0
% I
% Lys:
0
0
8
16
70
16
0
0
0
54
0
0
8
8
0
% K
% Leu:
24
0
0
39
0
0
8
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
31
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
85
0
0
0
0
0
0
0
8
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
0
0
16
0
% Q
% Arg:
0
0
8
0
8
85
0
0
0
8
0
0
54
0
0
% R
% Ser:
0
0
0
8
0
0
8
16
0
8
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
70
0
0
8
0
0
0
0
% T
% Val:
77
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _